B\u00e0i vi\u1ebft cung c\u1ea5p cho c\u00e1c b\u1ea1n h\u1ecdc sinh nh\u1eefng ki\u1ebfn th\u1ee9c c\u01a1 b\u1ea3n v\u1ec1 peptit nh\u01b0: kh\u00e1i ni\u1ec7m peptit l\u00e0 g\u00ec, c\u00e1c t\u00ednh ch\u1ea5t c\u1ee7a peptit… \u0111\u1ec3 c\u00e1c b\u1ea1n c\u00f3 th\u1ec3 h\u1ec7 th\u1ed1ng l\u1ea1i c\u00e1c ki\u1ebfn th\u1ee9c v\u1ec1 m\u00f4n h\u00f3a l\u1edbp 12.<\/p>\n

I \u2013 Kh\u00e1i ni\u1ec7m peptit l\u00e0 g\u00ec \u00a0v\u00e0 ph\u00e2n lo\u1ea1i<\/strong><\/h2>\n

1\/ Kh\u00e1i ni\u1ec7m peptit l\u00e0 g\u00ec<\/strong><\/h3>\n

– L\u00e0 li\u00ean k\u1ebft c\u1ee7a nh\u00f3m CO v\u1edbi nh\u00f3m NH gi\u1eefa 2 \u0111\u01a1n v\u1ecb\u00a0\u03b1-amino axit\u00a0\u0111\u01b0\u1ee3c 1 lo\u1ea1i l\u00e0 li\u00ean k\u1ebft peptit<\/p>\n

<\/p>\n

– V\u1edbi c\u00e2u h\u1ecfi Peptit l\u00e0 g\u00ec? Peptit l\u00e0 nh\u1eefng h\u1ee3p ch\u1ea5t c\u00f3 ch\u1ee9a t\u1eeb 2 \u0111\u1ebfn 50 g\u1ed1c\u00a0\u03b1-amino axit\u00a0v\u00e0 li\u00ean k\u1ebft v\u1edbi nhau b\u1eb1ng c\u00e1c li\u00ean k\u1ebft c\u1ee7a petit<\/p>\n

2\/ Ph\u00e2n lo\u1ea1i<\/strong><\/h3>\n

C\u00e1c peptit \u0111\u01b0\u1ee3c ph\u00e2n chia th\u00e0nh hai lo\u1ea1i:<\/p>\n

a) Oligopeptit<\/em>: bao g\u1ed3m c\u00e1c peptit trong \u0111\u00f3 c\u00f3 t\u1eeb 2 \u0111\u1ebfn 10 g\u1ed1c \u03b1-amino axit, ch\u00fang \u0111\u01b0\u1ee3c g\u1ecdi t\u01b0\u01a1ng \u1ee9ng v\u1edbi c\u00e1i t\u00ean l\u00e0 \u0111ipeptit, tripeptit\u2026
\nb) Polipeptit<\/em>: bao g\u1ed3m c\u00e1c peptit trong \u0111\u00f3 c\u00f3 t\u1eeb 11 \u0111\u1ebfn 50 g\u1ed1c \u03b1-amino axit. V\u00e0 polipeptit l\u00e0 c\u01a1 s\u1edf t\u1ea1o n\u00ean c\u00e1c protein<\/p>\n

II\u00a0\/ C\u1ea5u t\u1ea1o, \u0111\u1ed3ng ph\u00e2n v\u00e0 danh ph\u00e1p<\/strong><\/h2>\n

1\/ C\u1ea5u t\u1ea1o v\u00e0 \u0111\u1ed3ng nh\u00e2n c\u1ee7a peptit l\u00e0 g\u00ec<\/strong><\/h3>\n

– C\u1ea5u t\u1ea1o c\u1ee7a peptit l\u00e0 g\u00ec: C\u00e1c ph\u00e2n t\u1eed peptit \u0111\u01b0\u1ee3c h\u1ee3p th\u00e0nh t\u1eeb c\u00e1c g\u1ed1c \u03b1-amino axit \u0111\u01b0\u1ee3c n\u1ed1i v\u1edbi nhau b\u1edfi c\u00e1c li\u00ean k\u1ebft peptit theo 1 tr\u1eadt t\u1ef1 nh\u1ea5t \u0111\u1ecbnh: c\u00e1c amino axit \u0111\u1ea7u N c\u00f2n c\u00f3 nh\u00f3m NH_{2<\/sub>, v\u00e0 c\u00e1c amino axit \u0111\u1ea7u C c\u00f2n c\u00f3 nh\u00f3m COOH<\/p>\n}

– N\u1ebfu c\u00e1c ph\u00e2n t\u1eed peptit c\u00f3 ch\u1ee9a n g\u1ed1c \u03b1-amino axit kh\u00e1c nhau th\u00ec ta c\u00f3 s\u1ed1 \u0111\u1ed3ng ph\u00e2n c\u1ee7a peptit s\u1ebd l\u00e0 n!
\n– N\u1ebfu trong c\u00e1c ph\u00e2n t\u1eed peptit c\u00f3 i c\u1eb7p g\u1ed1c c\u1ee7a \u03b1-amino axit gi\u1ed1ng nhau th\u00ec ta c\u00f3 s\u1ed1 \u0111\u1ed3ng ph\u00e2n c\u1ee7a peptit l\u00e0<\/p>\n

2\/ Danh ph\u00e1p c\u1ee7a peptit<\/strong><\/h3>\n

T\u00ean c\u1ee7a c\u00e1c peptit \u0111\u01b0\u1ee3c t\u1ea1o th\u00e0nh b\u1eb1ng c\u00e1ch gh\u00e9p t\u00ean c\u1ee7a g\u1ed1c axyl c\u00e1c \u03b1-amino axit b\u1eaft \u0111\u1ea7u t\u1eeb \u0111\u1ea7u N, v\u00e0 k\u1ebft th\u00fac b\u1eb1ng t\u00ean c\u1ee7a c\u00e1c axit \u0111\u1ea7u C (ch\u00fang \u0111\u01b0\u1ee3c gi\u1eef nguy\u00ean). V\u00ed d\u1ee5:<\/p>\n

<\/p>\n

III\/<\/strong> T\u00ednh ch\u1ea5t c\u1ee7a peptit<\/strong><\/h2>\n

1\/ T\u00ednh ch\u1ea5t v\u1eadt l\u00ed c\u1ee7a peptit l\u00e0 g\u00ec?<\/strong><\/h3>\n

C\u00e1c peptit th\u00f4ng th\u01b0\u1eddng \u1edf th\u1ec3 r\u1eafn, ch\u00fang c\u00f3 nhi\u1ec7t \u0111\u1ed9 n\u00f3ng ch\u1ea3y cao v\u00e0 r\u1ea5t d\u1ec5 tan trong n\u01b0\u1edbc<\/p>\n

2\/ T\u00ednh ch\u1ea5t h\u00f3a h\u1ecdc c\u1ee7a peptit<\/strong><\/h3>\n

a) Ph\u1ea3n \u1ee9ng m\u00e0u biure<\/em><\/p>\n

– Trong ph\u1ea3n \u1ee9ng m\u1eabu c\u1ee7a biure ta c\u00f3: H_{2<\/sub>N\u2013CO\u2013NH\u2013CO\u2013NH2<\/sub>\u00a0+ Cu(OH)2<\/sub>\u00a0\u2192 ph\u1ee9c ch\u1ea5t c\u00f3 m\u00e0u t\u00edm \u0111\u1eb7c tr\u01b0ng
\n–\u00a0Amino axit, \u0111ipeptit\u00a0kh\u00f4ng cho lo\u1ea1i ph\u1ea3n \u1ee9ng n\u00e0y. V\u1edbi c\u00e1c tripeptit tr\u1edf l\u00ean c\u00f3 t\u00e1c d\u1ee5ng v\u1edbi Cu(OH)2<\/sub>\u00a0t\u1ea1o ra ph\u1ee9c ch\u1ea5t c\u00f3 m\u00e0u t\u00edm<\/p>\n}

b) Ph\u1ea3n \u1ee9ng th\u1ee7y ph\u00e2n c\u1ee7a peptit<\/em><\/p>\n

– \u0110i\u1ec1u ki\u1ec7n x\u1ea3y ra ph\u1ea3n \u1ee9ng th\u1ee7y ph\u00e2n: c\u00f3 ch\u1ea5t x\u00fac t\u00e1c axit ho\u1eb7c ki\u1ec1m v\u00e0 c\u1ea7n \u0111un n\u00f3ng
\n– S\u1ea3n ph\u1ea9m t\u1ea1o ra l\u00e0: c\u00e1c \u03b1-amino axit<\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

B\u00e0i vi\u1ebft cung c\u1ea5p cho c\u00e1c b\u1ea1n h\u1ecdc sinh nh\u1eefng ki\u1ebfn th\u1ee9c c\u01a1 b\u1ea3n v\u1ec1 peptit nh\u01b0: kh\u00e1i ni\u1ec7m peptit l\u00e0 g\u00ec, c\u00e1c t\u00ednh ch\u1ea5t c\u1ee7a peptit… \u0111\u1ec3 c\u00e1c b\u1ea1n… <\/p>\n","protected":false},"author":9,"featured_media":10338,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[471,450],"tags":[],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/onthitot.com\/wp-json\/wp\/v2\/posts\/10333"}],"collection":[{"href":"https:\/\/onthitot.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/onthitot.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/onthitot.com\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/onthitot.com\/wp-json\/wp\/v2\/comments?post=10333"}],"version-history":[{"count":0,"href":"https:\/\/onthitot.com\/wp-json\/wp\/v2\/posts\/10333\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/onthitot.com\/wp-json\/wp\/v2\/media\/10338"}],"wp:attachment":[{"href":"https:\/\/onthitot.com\/wp-json\/wp\/v2\/media?parent=10333"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/onthitot.com\/wp-json\/wp\/v2\/categories?post=10333"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/onthitot.com\/wp-json\/wp\/v2\/tags?post=10333"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}