Protein l\u00e0 m\u1ed9t chuy\u00ean \u0111\u1ec1 r\u1ea5t quan tr\u1ecdng trong ch\u01b0\u01a1ng tr\u00ecnh h\u00f3a h\u1ecdc l\u1edbp 12. V\u1edbi b\u00e0i vi\u1ebft n\u00e0y ch\u00fang ta c\u00f9ng nhau t\u00ecm hi\u1ec3u v\u1ec1 protein l\u00e0 g\u00ec v\u00e0 t\u00ednh ch\u1ea5t c\u1ee7a protein.<\/p>\n

\u00a0I\/ Kh\u00e1i ni\u1ec7m protein – ph\u00e2n lo\u1ea1i protein<\/h2>\n

1\/ Kh\u00e1i ni\u1ec7m protein l\u00e0 g\u00ec<\/h3>\n

Protein\u00a0l\u00e0 h\u1ee3p ch\u1ea5t c\u1ee7a nh\u1eefng\u00a0polipeptit cao ph\u00e2n t\u1eed<\/em>\u00a0 ch\u00fang c\u00f3 ph\u00e2n t\u1eed kh\u1ed1i t\u1eeb v\u00e0i ch\u1ee5c ngh\u00ecn \u0111\u1ebfn v\u00e0i tri\u1ec7u ph\u00e2n t\u1eed.<\/p>\n

2\/ Ph\u00e2n lo\u1ea1i protein<\/h3>\n

C\u00e1ch ph\u00e2n lo\u1ea1i c\u1ee7a protein l\u00e0 g\u00ec<\/p>\n

–\u00a0\u00a0\u00a0Protein \u0111\u01a1n gi\u1ea3n<\/strong>:\u00a0l\u00e0 protein \u0111\u01b0\u1ee3c t\u1ea1o th\u00e0nh t\u1eeb c\u00e1c\u00a0a\u00a0– amino axit\u00a0v\u00ed d\u1ee5 nh\u01b0\u00a0anbumin c\u1ee7a l\u00f2ng tr\u1eafng tr\u1ee9ng hay fibroin c\u1ee7a t\u01a1 t\u1eb1m,\u2026<\/em><\/p>\n

<\/p>\n

–\u00a0\u00a0\u00a0Protein ph\u1ee9c t\u1ea1p:\u00a0<\/strong>l\u00e0 protein \u0111\u01b0\u1ee3c t\u1ea1o th\u00e0nh t\u1eeb c\u00e1c protein \u0111\u01a1n gi\u1ea3n v\u1edbi th\u00e0nh ph\u1ea7n\u00a0c\u1ee7a \u201cphi protein\u201d<\/em>\u00a0nh\u01b0 l\u00e0 nucleoprotein ch\u1ee9a axit nucleic v\u00e0 lipoprotein ch\u1ee9a ch\u1ea5t b\u00e9o,\u2026<\/p>\n

\u00a0 II\/ C\u1ea5u tr\u00fac ph\u00e2n t\u1eed c\u1ee7a protein l\u00e0 g\u00ec<\/h2>\n

Protein \u0111\u01b0\u1ee3c t\u1ea1o th\u00e0nh b\u1edfi nhi\u1ec1u g\u1ed1c\u00a0a\u00a0– amino axit\u00a0kh\u00e1c nhau b\u1eb1ng c\u00e1c li\u00ean k\u1ebft peptit nh\u01b0:<\/p>\n

\u2026- NH \u2013 CH\u00a0 – C \u2013 NH \u2013\u00a0CH \u2013 C \u2013 NH \u2013 CH \u2013 C – \u2026<\/p>\n

R^{1\u00a0\u00a0\u00a0\u00a0\u00a0<\/sup>\u00a0O\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 R2<\/sup>\u00a0\u00a0\u00a0\u00a0\u00a0 O\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 R3<\/sup>_{\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/sub>O<\/p>\n}}

Hay\u00a0\u00a0\u00a0 ( – NH \u2013 CH\u00a0 – C \u2013 )_{n<\/sub><\/p>\n}

R^{i\u00a0\u00a0\u00a0\u00a0<\/sup>\u00a0\u00a0\u00a0O<\/p>\n}

Trong \u0111\u00f3 ta c\u00f3 :\u00a0n\u00a0l\u00e0 s\u1ed1 g\u1ed1c\u00a0a\u00a0– amino axit<\/p>\n

<\/p>\n

III\/ T\u00ednh ch\u1ea5t v\u1eadt l\u00ed c\u1ee7a protein l\u00e0 g\u00ec<\/h2>\n

Protein lu\u00f4n t\u1ed3n t\u1ea1i \u1edf 2 d\u1ea1ng ch\u00ednh l\u00e0:<\/p>\n

–\u00a0\u00a0D\u1ea1ng protein h\u00ecnh s\u1ee3i\u00a0<\/strong> (v\u1edbi d\u1ea1ng n\u00e0y protein kh\u00f4ng tan trong\u00a0n\u01b0\u1edbc<\/em>):\u00a0protein n\u00e0y c\u00f3 trong t\u00f3c, m\u00f3ng hay s\u1eebng.<\/em><\/p>\n

–\u00a0\u00a0D\u1ea1ng protein h\u00ecnh c\u1ea7u\u00a0<\/strong>( d\u1ea1ng protein n\u00e0y tan trong n\u01b0\u1edbc \u2192 t\u1ea1o dd keo<\/em>) :\u00a0protein n\u00e0y th\u01b0\u1eddng c\u00f3 trong l\u00f2ng tr\u1eafng tr\u1ee9ng hay hemoglobin c\u1ee7a m\u00e1u.<\/em><\/p>\n

IV\/ T\u00ednh ch\u1ea5t h\u00f3a h\u1ecdc<\/h2>\n

Trong h\u00f3a h\u1ecdc ch\u00fang ta c\u1ea7n t\u00ecm hi\u1ec3u c\u00e1c t\u00ednh ch\u1ea5t h\u00f3a h\u1ecdc c\u1ee7a protein l\u00e0 g\u00ec \u0111\u1ec3 c\u00f3 th\u1ec3 gi\u1ea3i t\u1ed1t c\u00e1c d\u1ea1ng b\u00e0i t\u1eadp v\u1ec1 protein<\/p>\n

1\/ Ph\u1ea3n \u1ee9ng th\u1ee7y ph\u00e2n c\u1ee7a protein l\u00e0 g\u00ec?<\/h3>\n

\n
• Khi th\u1ee7y ph\u00e2n trong m\u00f4i tr\u01b0\u1eddng axit \u2192 protein t\u1ea1o\u00a0c\u00e1c\u00a0<\/em>a<\/em>\u00a0– amino axit ban \u0111\u1ea7u<\/em><\/li>\n
• Khi th\u1ee7y ph\u00e2n trong m\u00f4i tr\u01b0\u1eddng baz\u01a1 \u2192 protein t\u1ea1o\u00a0mu\u1ed1i c\u1ee7a c\u00e1c\u00a0<\/em>a<\/em>\u00a0– amino axit ban \u0111\u1ea7u<\/em><\/li>\n<\/ul>\n

  2\/ Ph\u1ea3n \u1ee9ng m\u00e0u biure<\/h3>\n

  \n
  • Protein khi t\u00e1c d\u1ee5ng v\u1edbi Cu(OH)_{2<\/sub>s\u1ebd t\u1ea1o h\u1ee3p ch\u1ea5t\u00a0m\u00e0u t\u00edm (\u0111\u00e2y \u0111\u1eb7c tr\u01b0ng c\u1ee7a peptit)<\/em><\/li>\n}
  • Protein ph\u1ea3n \u1ee9ng s\u1ebd t\u1ea1o\u00a0k\u1ebft t\u1ee7a v\u00e0ng v\u1edbi dd HNO<\/em>3<\/sub><\/em>\u0111\u1eb7c.<\/em><\/li>\n<\/ul>\n

    <\/p>\n

    V\/ Kh\u00e1i ni\u1ec7m enzim v\u00e0 axit nucleic l\u00e0 g\u00ec<\/h2>\n

    \u00a0\u00a0 1\/ Enzin<\/h3>\n

    Enzin c\u00f3 b\u1ea3n ch\u1ea5t l\u00e0 protein v\u00e0 \u00a0enzim \u0111\u01b0\u1ee3c coi l\u00e0 ch\u1ea5t x\u00fac t\u00e1c sinh h\u1ecdc v\u1edbi hai \u0111\u1eb7c \u0111i\u1ec3m sau:<\/p>\n

    –\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0C\u00f3 t\u00ednh ch\u1ecdn l\u1ecdc r\u1ea5t cao v\u00e0 m\u1ed7i enzin l\u00e0m ch\u1ea5t x\u00fac t\u00e1c cho m\u1ed9t ph\u1ea3n \u1ee9ng nh\u1ea5t \u0111\u1ecbnh.<\/p>\n

    –\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0Trong ph\u1ea3n \u1ee9ng t\u1ed1c \u0111\u1ed9 c\u1ee7a ph\u1eb3n \u1ee9ng nh\u1edd x\u00fac t\u00e1c enzin l\u00e0 r\u1ea5t cao.<\/p>\n

    2\/ Axit nucleic<\/h3>\n

    \n
    • Axit nucleicl\u00e0 h\u1ee3p ch\u1ea5t cao ph\u00e2n t\u1eed c\u1ee7a nhi\u1ec1u g\u1ed1c nucleotit k\u1ebft h\u1ee3p nhau do c\u00e1c li\u00ean k\u1ebft photphodiese.<\/li>\n
    • M\u1ed7i m\u1ed9t g\u1ed1c nucleotit g\u1ed3m ba th\u00e0nh ph\u1ea7n k\u1ebft h\u1ee3p v\u1edbi nhau theo t\u1ec9 l\u1ec7 1:1:1 l\u00e0: Baz\u01a1 nit\u01a1 \u2013 pentoz\u01a1 \u2013 axit photphoric<\/li>\n<\/ul>\n

      Hi v\u1ecdng v\u1edbi nh\u1eefng ki\u1ebfn th\u1ee9c m\u00e0 ch\u00fang t\u00f4i cung c\u1ea5p \u0111\u00e3 gi\u00fap b\u1ea1n hi\u1ec3u h\u01a1n v\u1ec1 protein l\u00e0 g\u00ec v\u00e0 c\u00e1c t\u00ednh ch\u1ea5t c\u1ee7a n\u00f3.<\/p>\n","protected":false},"excerpt":{"rendered":"

      Protein l\u00e0 m\u1ed9t chuy\u00ean \u0111\u1ec1 r\u1ea5t quan tr\u1ecdng trong ch\u01b0\u01a1ng tr\u00ecnh h\u00f3a h\u1ecdc l\u1edbp 12. V\u1edbi b\u00e0i vi\u1ebft n\u00e0y ch\u00fang ta c\u00f9ng nhau t\u00ecm hi\u1ec3u v\u1ec1 protein l\u00e0 g\u00ec v\u00e0… <\/p>\n","protected":false},"author":9,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[471,450,408],"tags":[],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/onthitot.com\/wp-json\/wp\/v2\/posts\/10337"}],"collection":[{"href":"https:\/\/onthitot.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/onthitot.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/onthitot.com\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/onthitot.com\/wp-json\/wp\/v2\/comments?post=10337"}],"version-history":[{"count":0,"href":"https:\/\/onthitot.com\/wp-json\/wp\/v2\/posts\/10337\/revisions"}],"wp:attachment":[{"href":"https:\/\/onthitot.com\/wp-json\/wp\/v2\/media?parent=10337"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/onthitot.com\/wp-json\/wp\/v2\/categories?post=10337"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/onthitot.com\/wp-json\/wp\/v2\/tags?post=10337"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}